The Effects of CBD and Smoking
In one of the first studies, CBD was used to treat cigarette smokers with withdrawal symptoms and to curb cravings. In a similar study, 30 people addicted to cigarette smoking took 800mg of CBD and were monitored for cravings and withdrawal symptoms. In the study of what does CBD stand for and visual images of cigarettes were shown to the participants, and the CBD users showed significantly reduced pleasantness following exposure to them. This is important because tobacco imagery is a common trigger for cigarette smoking.
Results of a study comparing CBD to nicotine cigarettes
In a recent study, researchers compared the absorption rates of CBD and nicotine in smoking, and discovered that CBD was significantly more potent than nicotine. Smoking one cannabis cigarette contains 6.8% THC, or 54 mg of THC, while the average peak blood plasma CBD concentration occurred at a time of 11 minutes after smoking. THC absorption is much more efficient in smoking than oral administration. Similarly, CBD absorption is also significantly faster than in oral consumption, with a mean peak plasma concentration of 110 ng/mL, approximately one third of that for smoked cigarettes.
Effects on reaction time
To evaluate the effects of CBD and smoking on reaction time, we first assessed task performance. Participants were asked to perform a series of simple cognitive tasks with fixed intervals during the 6 hours following the smoking session. We also assessed the effects of THC on commission and omission errors. Interestingly, the effects of CBD and smoking on reaction time were not correlated with the smoking time. But, we found that marijuana had a significant effect on the stop reaction time.
In one study, participants received either a placebo or THC in their environment. Their performance was tested after two days. The mice were then challenged with two x 104 PFU of the SARS-CoV-2 virus. They were monitored twice a day for clinical disease and weighed once a day. Five days after the virus challenge, they were humanely killed and lung tissue was collected.
Effects on motor performance
A pilot study investigated the effect of CBD-rich marijuana on driving ability. In a double-blind, placebo-controlled design, subjects smoked CBD-rich marijuana and then completed neurocognitive and psychomotor tests. During the second day, motor time was not affected. While this was an unexpected finding, it does support the benefits of CBD-rich marijuana for the treatment of ADHD and other symptoms.
Results from the pilot study were not conclusive due to some methodological problems, although the effect of CBD on motor performance was observed in both groups. The pilot study found that CBD did not impair the ability to drive in a car with an BAC of 0.02% (1.12 cm) or 0.05% (2.4 cm)24. However, the effects of smoking and CBD on motor performance were not statistically significant. This suggests that both methods have significant effects, although further studies should be conducted to confirm or rule out these effects.
In the pilot study, CBD-treated participants were administered a placebo joint. The test participants were then given a joint containing CBD or a placebo, and they smoked it within 10 minutes. After smoking the joint, they were then taken to a first examination room, where they took blood samples. This was repeated seven to fourteen days later. The second test day was completed nine days later.
Free THC levels in capillary blood
In a recent study, researchers investigated the effects of marijuana with CBD on driving ability. The researchers measured the levels of THC and free CBD in capillary blood samples taken from participants who smoked a joint containing 500 mg of marijuana. After the smoking session, the participants took the Vienna Test System TRAFFIC, a test that assesses concentration performance, reaction time, and behavior under stress. They also completed tests to measure balance and coordination. Vital signs such as blood pressure, heart rate, and oxygen saturation were also measured.
Despite these findings, the bioavailability of THC and CBD is remarkably similar. Both THC and CBD have a similar bioavailability, with a C max of 11 to 45 ng/mL and a Tmax of about 60 minutes after smoking. However, there are a few differences between the two substances. CBD is slightly more bioavailable than THC, while THC is less absorbed in the blood.